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CHEMOKINE CXCL12
Descriptors Found:
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DeCS
Descriptor
English
:
Chemokine CXCL12
Descriptor
Spanish
:
Quimiocina CXCL12
Descriptor
Portuguese
:
Quimiocina CXCL12
Synonyms
English
:
CXCL12 Chemokine
Stromal Cell-Derived Factor-1beta
Tree Number:
D12.644.276.374.200.120.600
D12.776.467.374.200.120.600
D23.125.300.120.600
D23.469.200.120.600
D23.529.374.200.120.600
Definition
English
:
A CXC chemokine that is chemotactic for
T-LYMPHOCYTES
and
MONOCYTES
. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.
History Note
English
:
2008(1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52780
Unique Identifier:
D054377
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS